#10755 NTR: terminal web

[KM Van Auken]

Hi,
I'd like to request a new CC term 'terminal web'.

GO:0030864 cortical actin cytoskeleton
is_a GO:new terminal web

Possible definition: An actin-rich cytoskeletal network located beneath the microvilli of the apical plasma membrane of polarized epithelial cells. In addition to actin filaments, the terminal web may contain actin-binding proteins, myosin motor proteins, and intermediate filaments. The terminal web can function as a contractile structure that influences the spatial distribution of microvilli as well as the development and morphogenesis of tissues containing polarized epithelial cells.

References:
PMID:7511618
PMID:19437512
PMID:24677443
http://en.wikipedia.org/wiki/Terminal_web

Thanks,
--Kimberly

[Paola Roncaglia]

Hi Kimberly, done:

[Term]
id: GO:1990357
name: terminal web
namespace: cellular_component
def: "An actin-rich cytoskeletal network located beneath the microvilli of the apical plasma membrane of polarized epithelial cells. In addition to actin filaments, the terminal web may contain actin-binding proteins, myosin motor proteins, and intermediate filaments. The terminal web can function as a contractile structure that influences the spatial distribution of microvilli as well as the development and morphogenesis of tissues containing polarized epithelial cells." [GOC:kmv, http://en.wikipedia.org/wiki/Terminal_web, PMID:19437512, PMID:24677443, PMID:7511618]
is_a: GO:0030864 ! cortical actin cytoskeleton

Thanks,
Paola