#10661 Add capable_of for GO:0002178 ! palmitoyltransferase complex

[Chris Mungall]

[Term]
id: GO:0002178
name: palmitoyltransferase complex
namespace: cellular_component
def: "A protein complex with palmitoyltransferase activity." [GOC:hjd]
is_a: GO:0043234 ! protein complex
created_by: hjd
creation_date: 2010-12-03T10:49:17Z

should have equiv axiom with capable_of to

• GO:0016409 ! palmitoyltransferase activity

[Harold J. Drabkin]

Does this really need this; it already has capable_of to its child, serine C-palmitoyltransferase activity

[Chris Mungall]

Sorry Harold, don't understand your response.

I'm not seeing the axiom you're seeing.

I went ahead and added the equivalence axiom and closing this. Reopen if you think it's a mistake. r19581

[Chris Mungall]

Oh wait, is this what you're referring to:

[Term]
id: GO:0031211
name: endoplasmic reticulum palmitoyltransferase complex
def: "A dimeric complex of the endoplasmic reticulum that catalyzes S-palmitoylation, the addition of palmitate (C16:0) or other long-chain fatty acids to proteins at a cysteine residue." [GOC:jh]
is_a: GO:0002178 ! palmitoyltransferase complex
is_a: GO:0044425 ! membrane part
is_a: GO:0044432 ! endoplasmic reticulum part
is_a: GO:1990234 {is_inferred="true"} ! transferase complex
*intersection_of: GO:0043234 ! protein complex
*intersection_of: capable_of GO:0016409 ! palmitoyltransferase activity
relationship: part_of GO:0005789 ! endoplasmic reticulum membrane

The equivalence axiom is obviously too strong here. I'm fixing.

[Chris Mungall]

Better?

[Term]
id: GO:0031211
name: endoplasmic reticulum palmitoyltransferase complex
namespace: cellular_component
def: "A dimeric complex of the endoplasmic reticulum that catalyzes S-palmitoylation, the addition of palmitate (C16:0) or other long-chain fatty acids to proteins at a cysteine residue." [GOC:jh]
is_a: GO:0002178 {is_inferred="true"} ! palmitoyltransferase complex
is_a: GO:0044425 {is_inferred="true"} ! membrane part
is_a: GO:0044432 {is_inferred="true"} ! endoplasmic reticulum part
is_a: GO:1990234 {is_inferred="true"} ! transferase complex
intersection_of: GO:0043234 ! protein complex
intersection_of: capable_of GO:0019706 ! protein-cysteine S-palmitoyltransferase activity
intersection_of: part_of GO:0005789 ! endoplasmic reticulum membrane

[Chris Mungall]

While we're here:

[Term]
id: GO:0002179
name: homodimeric serine palmitoyltransferase complex
namespace: cellular_component
def: "A homodimeric complex which transfers a palmitoyl group onto serine, forming 3-dehydro-D-sphinganine." [GOC:hjd]
comment: This complex occurs primarily in bacteria.
is_a: GO:0002178 ! palmitoyltransferase complex
created_by: hjd
creation_date: 2010-12-03T10:50:59Z

Is this the activity?

• GO:0004758 ! serine C-palmitoyltransferase activity [DEF: "Catalysis of the reaction: L-serine + H(+) + palmitoyl-CoA = 3-dehydrosphinganine + CO(2) + CoA."]

[Harold J. Drabkin]

yes; that was my question before I was going to add it.
Yes: 4758 is the correct activity for 2179

[Chris Mungall]

Harold, did you mean to close the ticket? You didn't add the axiom.

I'm adding it now (note: as subclass axiom, not equivalence)...

...done. r19877