#676 problem mapping for glutamate--cysteine ligase regulatory s

[Valerie Wood]

This regulatory subunit has the EC number(EC 6.3.2.2) in Uniprot (see for e.g. O94246,
but it the regulatory subunit not the catalytic subunit.

If it does have this annotation, it needs to have "contributes to" which is not possible within the mapping files.

better mappings for the regulatory subunit would be
enzyme regulator activity
glutamate-cysteine ligase catalytic subunit binding
glutamate-cysteine ligase complex

v

[Midori Harris]

In ec2go, EC 6.3.2.2 is mapped to the molecular function term glutamate-cysteine ligase activity (GO:0004357), which is fine. The problem is with UniProt annotations to the regulatory subunit, which can't be addressed by changing the ec2go mapping file. So I've changed the summary.

m

[rach_huntley]

This annotation has disappeared.