#7 Error on loading site

[Nuve Nai]

I Get the following error when I open my site. I think it
has something to do with Saving Updates and the
session.xml file and sContent.
please help

Microsoft VBScript runtime error '800a0046'

Permission denied

/engine/functions.asp, line 87 Unable to load the file ''.
Reason: The parameter is incorrect.
Line: 0
Line Pos: 0