Dr Fit enables to automatically fit a curve to your experimental dose-response data. The data, which should be saved in .xls files, is uploaded through the software which then automatically models it. The resulting curve can be saved in a high resolution figure or as a matlab figure. Responses/Effects can also be interpolated/extrapolated at various doses.
Dr Fit, associated method, and our new multi-phasic model have been described in the following paper:
G. Y. Di Veroli, C. Fornari, I. Goldlust, G. Mills, S. B. Koh, J. L. Bramhall, F. M. Richards, and D. I. Jodrell, βAn automated fitting procedure and software for dose-response curves with multiphasic features,β Sci. Rep., vol. 5, p. 14701, 2015 (http://www.nature.com/articles/srep14701)
software (green button or):
https://sourceforge.net/projects/drfit/files/Executable/
user's guide:
https://sourceforge.net/projects/drfit/files/USER%20GUIDE/
examples:
https://sourceforge.net/projects/drfit/files/EXAMPLES/
Features
- Visualize dose-response data
- Fit regular mono-phasic dose-response curves (Hill equation)
- Fit multi-phasic dose-response curves
- Save results in high quality figures
- Interpolate/extrapolate responses
- Calculate effective concentrations (e.g. GI50)
- Extract model parameters