Read Me

DRUG PACKAGE INSERT MASHUP PROTOTYPE

A prototype of a system that uses Semantic Web techology and natural
language processing to identify and present drug mechanism information
that updates or expands upon statements present in drug package
inserts. These files are sufficient to run the prototype discussed in
the following short conference paper: 

Boyce, R. Conway, M. “Leveraging the Semantic Web and Natural Language
Processing to Enhance Drug-mechanism Knowledge in Drug Product
Labels,” Proceedings of the 2010 ACM International Health Informatics
Symposium. Arlington VA. November 2010.

REQUIREMENTS:
Python > 2.3 : www.python.org
SPARQLWrapper : http://sparql-wrapper.sourceforge.net
simplejson : http://pypi.python.org/pypi/simplejson/


EXAMPLE RUN:
$ python labelMashupDemonstration.py > log.txt

Five mashups are created with this prototype; see the following files
in the 'output' folder:

dikb-label-mashup-escitalopram.html (additional evidence)
dikb-label-mashup-mexiletine.html (additional evidence)
dikb-label-mashup-clozapine.html (additional evidence; note, the script does not correctly escape two quote symbols '"' on line 53; you can view the file once you manually escape the quotes)
dikb-label-mashup-modafinil.html (no additional evidence)
dikb-label-mashup-citalopram.html (no additional evidence; note, the script does not correctly escape two quote symbols '"' on line 53; you can view the file once you manually escape the quotes)

Please contact Richard Boyce at rdb20@pitt.edu if you have further
questions.

------------------------------------------------------------------
PROTOTYPE LICENSE 
------------------------------------------------------------------

The prototype (labelMashupDemonstration.py) is copyright (C) 2010
Richard Boyce, Henk Harkema, Mike Conway -- University of
Pittsburgh. All rights reserved. 

The Drug Interaction Knowledge Base (DIKB) is (C) Copyright 2005-2010
by Richard Boyce. All rights reserved.

Use, reproduction, and preparation of derivative works are permitted.
Any copy of this software or of any derivative work must include the
above copyright notice and this paragraph.  Any distribution of this
software or derivative works must comply with all applicable United
States export control laws.  This software is made available as is,
and Richard Boyce, Mike Conway, and the University of Pittsburgh
disclaim all warranties, express or implied, including without
limitation the implied warranties of merchantability and fitness for a
particular purpose, and notwithstanding any other provision contained
herein, any liability for damages resulting from the software or its
use is expressly disclaimed, whether arising in contract, tort
(including negligence) or strict liability, even if Richard Boyce,
Mike Conway, or the University of Pittsburgh is advised of the
possibility of such damages.

------------------------------------------------------------------
RIALTO TOOLKIT LICENSE 
------------------------------------------------------------------
The Rialto Javascript toolkit is used to render an a message box in
this demo. Its license information is as follows:

Copyright (c) 2005-2009, Improve
All Rights Reserved.
Licensed under the Apache License version 2.0 or above.
For more information on licensing, see:
http://www.apache.org/licenses/