#2427 ntrs: protein kinase inhibitors

[Midori Harris]

all mentioned in PMID:8529881

all can have link has_role protein kinase inhibitor (CHEBI:37699), or specific types of CHEBI:37699 could be added (if necessary) and used as noted

name: KT5720
CAS number: 108068-98-0
http://pubchem.ncbi.nlm.nih.gov/compound/3844
has_role: cAMP-dependent protein kinase inhibitor (CHEBI:new)

name: KT5823
CAS number: 126643-37-6
PMID:10922374
http://pubchem.ncbi.nlm.nih.gov/compound/3843
has_role: cGMP-dependent protein kinase inhibitor (CHEBI:new)

name: KT5926
CAS number: 126643-38-7
http://pubchem.ncbi.nlm.nih.gov/compound/122126 or http://pubchem.ncbi.nlm.nih.gov/compound/46839350 ?
PMID:2325635
has_role: myosin light chain kinase inhibitor (CHEBI:79091 or CHEBI:75997 (what's the difference? should they merge?))

[Gareth Owen]

Now done:
KT 5720 (CHEBI:85085) has_role EC 2.7.11.11 (cAMP-dependent protein kinase) inhibitor (CHEBI:85094)

KT 5823 (CHEBI:85102) has_role EC 2.7.11.12 (cGMP-dependent protein kinase) inhibitor (CHEBI:85113)

KT 5926 (CHEBI:85114) has_role EC 2.7.11.18 (myosin-light-chain kinase) inhibitor (CHEBI:78763)

[CHEBI:79091 and CHEBI:75997 have now been merged as they were indeed the same thing - EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor (parent id is CHEBI:79091), but EC 2.7.11.18 (myosin-light chain kinase) inhibitor (CHEBI:78763) is a different entity]

Best regards,
Gareth