mplement the colocalization method described here:
http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T04-4FGX840-1&_coverDate=07%2F15%2F2005&_alid=473487525&_rdoc=1&_fmt=&_orig=search&_qd=1&_cdi=4852&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=f694a34de0b9f65b06faee37b21612cb
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