Hi all,
I would like to calculate the dielectric constant of a protein in order to use the good value for the solvation energy calculations because my active site is solvent exposed.
Different values ranging from 4 to 20 were used in the literature. Is it possible to calculate the distribution of epsilon of the protein. 
Best regards

Dr. Safwat Abdel-Azeim Postdoc (Computational  Chemistry)
(CREST fellow)  Prof. Keiji Morokuma group
Fukui Institute for Fundamental Chemistry, Kyoto University
Takano Nishihiraki-cho 34-4, Sakyo-ku
Kyoto, 606-8103, Japan