this one was working before with cdk1.4
String smirks = "[H][C;R1:3]([H:2])([#6;X4:5])[#6;X4:6]>>[H:2][C;R1:3]([#6;X4:5])([#6;X4:6])O"; String smi = "CC1(C)C2CC1C(CO)=CC2";
Examples are also provided as short, self-contained Java Unit Test:
https://github.com/mguetlein/TestAmbitSmarts/blob/master/src/test/java/org/kramerlab/test/TestAmbit.java
Envipath ids:
rule3803
c0630
It is right that the reaction is not applicable for target substrate because of the condition [C;R1:3]
which says that the carbon atom takes part exactly in one ring.
The target molecule (substrate) is a bridged system and the atom tried to matched actually takes part in more than one ring.