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A tool for supporting pharmacogenomics data analysis
We developed DMET-Analyzer a tool for the automatic association analysis among the
variation of the patient genomes and the clinical conditions of
patients, i.e. the different response to drugs.
The proposed system allows: (i) to automatize the workflow of
analysis of DMET-SNP data avoiding the use of multiple tools; (ii) the
automatic annotation of DMET-SNP data and the search in existing databases of SNPs (e.g. dbSNP), (iii) the association of SNP with pathway through the search in PharmaKGB, a major knowledge base for pharmacogenomic studies. ...
MAGMA: Multiobjective Analyzer for Genetic Marker Acquisition
A genetic algorithm for generating SNP tiling paths from a large SNP database
based on the competing objectives of cost (number of SNPs) and coverage (haplotype blocks):
Hubley R., Zitzler