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...This Docker image allows you to create Flask web applications in Python that run with uWSGI and Nginx in a single container. The combination of uWSGI with Nginx is a common way to deploy Python Flask web applications. It is widely used in the industry and would give you decent performance. If you are starting a new project, you might benefit from a newer and faster framework based on ASGI instead of WSGI (Flask and Django are WSGI-based). Also, if you want to use new technologies like WebSockets it would be easier (and possible) with a newer framework based on ASGI, like FastAPI or Starlette. ...

Flask-SQLAlchemy is an extension for Flask that adds support for SQLAlchemy to your application. It simplifies using SQLAlchemy with Flask by setting up common objects and patterns for using those objects, such as a session tied to each web request, models, and engines. Flask-SQLAlchemy does not change how SQLAlchemy works or is used. See the SQLAlchemy documentation to learn how to work with the ORM in depth. The documentation here will only cover setting up the extension, not how to use SQLAlchemy.

...Restless is BYOD (bring your own data) and hence, works with almost any ORM/data source. If you can import a module to work with the data & can represent it as JSON, Restless can work with it. Restless is small & easy to keep in your head. Common usages involve overriding just a few easily remembered method names. Total source code is an under a thousand lines of code.