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Flask is a lightweight WSGI web application framework designed to help developers get started with their web applications quickly and easily with the ability to scale up to complex applications. Being a “micro” framework does not mean that your whole web application must fit into a single Python file (although it can) or that it be limited; rather it means that Flask aims to keep the core simple but extensible.

web.py is a web framework for Python that is as simple as it is powerful. web.py is in the public domain, you can use it for whatever purpose with absolutely no restrictions. web.py was originally published while Aaron Swartz worked at reddit.com, where the site used it as it grew to become one of the top 1000 sites according to Alexa and served millions of daily page views. “It’s the anti-framework framework. web.py doesn’t get in your way,” explained founder Steve Huffman. (The site was rewritten using other tools after being acquired by Condé Nast.) The latest stable release 0.62 only supports Python >= 3.5. If you are still using Python 2.7, then please use web.py version 0.51 which is intended to be our last release that supports Python 2.

...Less time debugging. Designed to be easy to use and learn. Less time reading docs. Minimize code duplication. Multiple features from each parameter declaration. Fewer bugs. Get production-ready code. With automatic interactive documentation. Based on (and fully compatible with) the open standards for APIs: OpenAPI (previously known as Swagger) and JSON Schema. If you are building a CLI app to be used in the terminal instead of a web API, check out Typer. Typer is FastAPI's little sibling. And it's intended to be the FastAPI of CLIs. ...

Build fast, run fast with Sanic! Sanic is a Python 3.6+ web server and web framework designed to go fast. It provides a way to get a highly performant HTTP server up and running fast, while also making it easy to build, expand, and eventually scale. Sanic aspires to be as simple as possible while delivering the performance that you require. It allows the usage of the async/await syntax added in Python 3.5, so your code is guaranteed to be non-blocking and speedy.

TurboGears is a hybrid web framework able to act both as a Full Stack framework or as a Microframework. TurboGears helps you get going fast and gets out of your way when you want it! TurboGears can be used both as a full stack framework or as a microframework in single-file mode. TurboGears 2 is built on top of the experience of several next-generation web frameworks including TurboGears 1 (of course), Django, and Rails. All of these frameworks had limitations that frustrated us, and TG2 was built as an answer to that frustration. ...