NWic is a .NET web development framework ported from a Java open-source project called jWic. NWic helps software developers building rich-client style web applications using the MVC design pattern. The UI is updated using the integrated AJAX features.
The emerge toolkit is a state-preserved web development framework. Build your whole application in one easy place. Uses O/R Mapping on the back-end, and Comet-style sockets on the front. http://emergetk.com
A MVC oriented client-server web framework written in C and JavaScript for Apache HTTP servers. The server executes models and the built-in template engine creates the view. The client-side is a JS API, and makes communication with the server easy.