Wiso is a Iso web framework written in HTML/Javascript/CSS based on the Prototype framework. Wiso can be part of a 2.5D (isometry) web game engine for web games.
Seam(less) is an open-source web application framework created by Hakano. Seam(less) provides a powerful toolkit for building Web2.0, Ajax-enabled web applications using declarative markup.
The emerge toolkit is a state-preserved web development framework. Build your whole application in one easy place. Uses O/R Mapping on the back-end, and Comet-style sockets on the front. http://emergetk.com
Echo2 is the next-generation of the Echo Web Framework, a platform for developing web-based applications that approach the capabilities of rich clients. http://www.nextapp.com/platform/echo2/echo/ It is based on AJAX technology. This version includes com
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