Aquarium is a framework for creating highly-dynamic, custom Web application in Python. It offers convenient libraries, tight integration with Cheetah, adaptors for various Web environments, and a convenient approach to Web development.
TurboGears 2 is a web framework, but unlike some of its competitors, it's not a monolithic unit, it's a collection of libraries, WSGI components, and web development tools that works well together and is configured to provide a great out of the box.