... Disk etc whereas your USB Peripheral Devices will work normal including USB Mouse, Keyboard, Webcam etc Also Virus Problem is Eliminated since no data is transferred it protects us from Viruses
With Registry & Command Prompt Tools , Unauthorized Code Execution is Eliminated since we can disable command prompt & registry no one can write commands/registry entries manually and execute it Also Protection From Hackers since they can execute some codes via command prompt which may retrieve our data