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InterPython (stands Python InterOperability) is a .NET library that allows a python interpreter to be "embedded" in your .NET programs, and gives you (almost) transparent access to python libraries and services in .NET programs. Great for GUIs, etc.
FXPy is a Python extension module that provides an interface to the cross-platform FOX GUI library. It is no longer under development, but the last release is compatible with FOX 1.0 and Python 2.2.
Baum is a Qt based GUI application framework with a built in python interpreter. Baum allows rapid creation of GUI's with simple python scripts. Programmers can re-use available python and widget library.
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An environment (library + IDE) that emulates Delphi but uses python as the programming language and wxPython as the graphical API. Starting with the library, we have a set of modules/classes that emulates the units/classes of the famous VCL.
The PyQt4D (Python Qt for Designer) is an Open Source Project making Qt Designer full-featured RAD (Rapid Application Development) tool to develop data-aware two- or multi-tier applications using Python language and Qt library.
Guide is a Pythonlibrary for UI layout and data-binding which is cross-platform and supports multiple UI libraries. It allows users to quickly iterate on design and functionality of UIs using an xml markup-language.
SoGui est un toolkit graphique C++ multiplate-forme (Windows/X11). SoGui permet donc de créer des interfaces GUI de façon portable sur Windows, GNU/Linux, *BSD, etc. SoGui est aussi utilisable en C et en Python.