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yuik is an abstract widget library for creating GUIs. The actual frontend can be chosen at runtime which allows the program to run under Tk, as a shell program, and even as a web-application. More frontends like an irc-bot, wxWidgets, or XUL are planned.
...The tool should provide a simple way to log the user's mouse movements in the background for (later) analysis. Currently only for Mac OS X (ObjC & Cocoa), planned to make platform independent with Python. It consists out of two
wxBrowser is an application browser based on the wxWidgets GUI framework. It's similar to a regular old web browser only, instead of reading HTML and displaying content it reads XML and executes presentation logic (wxPython) in a client side application.
Ophidian is a Python module created to easily develop wxPython user interfaces. Ophidian provides wrapper classes to transparently load XRC resources and access the user controls inside them, with a minimum of coding effort.
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ACDK - Artefaktur Component Development Kit - is a platform independent C++-framework similar to Java or C#/.NET for generating distributed and scriptable components and applications.
Educational game framework supporting board games, strategy games, and other grid-based game boards. Currently uses Python/wxPython as the application language/library. C++ libs included to help create AI for the various games.
InterPython (stands Python InterOperability) is a .NET library that allows a python interpreter to be "embedded" in your .NET programs, and gives you (almost) transparent access to python libraries and services in .NET programs. Great for GUIs, etc.
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GILA: Graphical Interface Logistics Application. GILA is meant to provide a configurable, object oriented user interface, that is capable of interacting with existing applications via user configuration.
FXPy is a Python extension module that provides an interface to the cross-platform FOX GUI library. It is no longer under development, but the last release is compatible with FOX 1.0 and Python 2.2.
Full blender integrated documentation and multi-language translation (help) > Python script for Blender, a free open source 3D content creation suite, available for all major operating systems under the GNU General Public License.
Baum is a Qt based GUI application framework with a built in python interpreter. Baum allows rapid creation of GUI's with simple python scripts. Programmers can re-use available python and widget library.
The PyQt4D (Python Qt for Designer) is an Open Source Project making Qt Designer full-featured RAD (Rapid Application Development) tool to develop data-aware two- or multi-tier applications using Python language and Qt library.
Threadmill is a compact and powerful set of tools that integrates parsing and intuitive multithreadability with command-line programs written in the Python programming language.
Guide is a Python library for UI layout and data-binding which is cross-platform and supports multiple UI libraries. It allows users to quickly iterate on design and functionality of UIs using an xml markup-language.
An environment (library + IDE) that emulates Delphi but uses python as the programming language and wxPython as the graphical API. Starting with the library, we have a set of modules/classes that emulates the units/classes of the famous VCL.
Wrapper of Tkinter python module. Provides useful widgets created especially with sw-developers and electronic engineers in mind, who need simple and functional GUI for controlling statuses, logging events, or testing programs at the initial stage.
PyAID is an abstract and neutral representation of user interface and interaction. These definitions can be automatically rendered into actual UI toolkits by the view renderer such as GTK+, newt, WxWindow, etc.
a tool-kit for creating "web 2.5 generation", include several useful stuff to work with semantic web (otology editor, gui for sparql query, ontology components...) and design RIAs's gui visually (html + ajax based apps, flash based apps,...)