An extremely configurable portable GUI email and news client for Windows/Unix (including OS X) with IMAP, POP3, SMTP, and NNTP support, SSL, flexible address database, Python scripting, powerful filtering, and many other features for advanced users.
Abusenetstreamer lets you stream a video file from usenet including (and automating) all the tasks like uudecoding and decompression. Specify a nzb file and start watching after a small buffering periode.
QNNTPGet is a program for downloading multipart binaries from newsservers. It is written in python using the PyQT bindings. It can work as a stand alone client but works best as a front end to leafnode.