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The Null-modem emulator (com0com) is a kernel-mode virtual serial port driver for Windows. You can create an unlimited number of virtual COM port pairs and use any pair to connect one COM port based application to another. The HUB for communications (hub4com) allows to receive data and signals from one COM or TCP port, modify and send it to a number of other COM or TCP ports and vice versa.
Ponticulus (a virtual COM-port over TCP/IP redirector) allows synchronous connecting and disconnecting to a remote serial port (e.g. on an embedded device). It was initially based on com2tcp, part of the com0com project. (http://com0com.sourceforge.net/)