New to Google Cloud? Get $300 in credits to explore Compute Engine, BigQuery, Cloud Run, Gemini Enterprise Agent Platform, and more.
Start your next project with $300 in free Google Cloud credit. Spin up VMs, run containers, query petabytes in BigQuery, or build agents with Gemini Enterprise Agent Platform. Once your credits are used, keep building with 20+ always-free tier products including Compute Engine, Cloud Storage, GKE, and Cloud Run functions. No commitment required—just sign up and start building.
Claim $300 Free
Stop vibe-debugging.
Plug Claude into your app's actual errors.
AppSignal's MCP server hands Claude, Cursor, or Zed your real errors, traces, and the deploy that shipped them. AI writes the fix; you review the diff.
This program was developed as a help in establishing pharmaceutical equivalence by use of FDA f2 coefficient. It was designed to help with f2 computation in cases when intra- and inter-batch variability is large, namely RSD>10%. The use of statistical bootstrap technique allows to implement confidence interval (CI) into the f2 coefficients resulting in overcoming of their major drawback in the original metrics. The algorithm provides possible “worst case scenario” of f2 values, thus...