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JackFX is a python module for midi control and realtime audio effects processing built using the Jack Audio Connection Kit. Effects are stackable, and can be chained in any configuration with only a few lines of python code.
Capricciotools is a set audio related tools to be ran on a headless linux server. This includes: automatic transcoding of flac files to mp3 and ogg vorbis files; a cd-ripper (to flac, including freedb/musicbrainz tag lookup).
A GTK/Glade based management interface for the PODxt (Live and Pro) from Line 6. Written in Python for Linux.
It requires a MIDI connection to the device and the Line6 USB driver from http://www.tanzband-scream.at/line6/
Amakode is a script for Amarok to transcode music. It has minimal installation dependencies: it is written purely in python (so it runs everywhere) and uses external executables to do the grunt work (which you probably already have installed anyway)
A real time sound processing software. It can be used both, for general audio processing/editing and as a fuzzbox. Based on a very flexible plug-in system, it has been coded in python and currently uses portaudio for sound input/output.
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MyPy Jukebox is a project to build a linux based touch screen jukebox. Currently the application is using mysql for backend database storage and xmms for front end music playing. MyPy itself is written in python.
BtXmms is a simple program that permits to control your xmms mp3 player via bluetooth with whatever mobile device that is provided of a JVM and bluetooth (such as Nokia 6630 ecc) .
gmocp (gnome moc player) is a gtk-based frontend for the moc player (music on console). It allows to you to play, pause, next, previouse, toggle shuffle, toggle repeat and control the playlist elements.
Sonar 2D is a live signal processing application where an audio signal is used to navigate between 'zones' in a virtual 2d space. Each zone represents a given processing module, which when activated will be applied to the sound.