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A Python-based development and testing framework for smart contracts
...Once installed, you will never have to activate a virtual environment prior to using Brownie. Brownie documentation is hosted at Read the Docs. Use tox to run the complete suite against the full set of build targets, or pytest to run tests against a specific version of Python. If you are using pytest you must include the -p no:pytest-brownie flag to prevent it from loading the Brownie plugin.
Woke is a Python-based development and testing framework for Solidity
Woke is a Python-based development and testing framework for Solidity. A testing framework for Solidity smart contracts with Python-native equivalents of Solidity types and blazing-fast execution. A property-based fuzzer for Solidity smart contracts that allows testers to write their fuzz tests in Python. See examples and documentation for more information.