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Python+Numpy+OpenGL, scalable and beautiful scientific visualization
Glumpy is a Python library that simplifies the development of high-performance, interactive OpenGL visualizations. It abstracts complex OpenGL tasks into Pythonic constructs, making it easier for scientists, artists, and developers to harness the power of the GPU for real-time rendering and data visualization. Glumpy is particularly well-suited for rapid prototyping of graphical applications, and its integration with NumPy and shader programming makes it a powerful tool for both research and creative exploration.
Crystal Space is an Open Source 3D SDK for Unix, Windows, and MacOS/X. It renders with OpenGL and features GLSL shaders, CG shaders, deferred rendering, dynamic shadows, bullet based physics library, terrain engine, skeleton based animation meshes, exporter for Blender, portals, etc...