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WebPython is a web-application development toolkit, written in Python. It contains a portable object-relational database layer, a Python-object persistence system and a templating engine, among other stuff.
The CCC Language is yet another programming language. It is platform-independent, compact, and robust. Supports many SQL engines, has own ISAM DB engine, has terminal mode and more UI-s, is object-oriented, but it is compiled and not interpreted.
A content generation engine written in Python used for generating content for HTML and textual output. Integrates with Apache to form a web framework that uses XML templates and can embed Python.
NiL is a modular multi-purpose gaming engine including a multiplayer worm game a little like quake, except it's 2d and a little like worms except it's realtime.
Pure Python implementation of GOLD Parser Engine.
GOLD Parser Engine is a LALR(1) parser with DFA tokenizer.
It uses compiled grammar table generated by GOLD Parser Builder (not included - available on http://www.devincook.com/goldparser)
Luxor is an open-source XML UI Language (XUL) toolkit in Java that lets you build UIs using XML and includes a web server, a portal engine (supporting RSS), a template engine (Velocity), a scripting interpreter (Python) and more.
PyBuzz is a machine plugin for the Buzz Modular Tracker that acts as a host for python scripts using the python interpreter engine developed by http://www.python.org.
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The purpose of Element is to provide a powerful, high-level object-oriented 2D engine primarily intended for the development of games through the Python programming language.
LucidEngine is a simple layer over MIDP compatible phones that will let you write simple and old fashioned games using a specific language.
Every game you'll develop will basically work on all the devices (even not phones) LucidEngine as been ported.
RuleCore is an event-driven reactive (ECA style) rule engine with GUI tools, all written in Python. RuleCore triggers actions by detecting complex patterns of events. RuleCore supports Tibco Rendezvous, WebSphere MQ, XML-RPC or plain sockets.
Metakit is an efficient database library with a small footprint. It's a cross between flat-file, RDBMS, and OODBMS.
Keywords: structured storage, transacted, load on-demand, portable, C++, Python, Tcl, instant schema versioning.
Falconer-Try Studios is developing this new gaming engine for 2D, 3D and soon VR environments. It will be best for RTS and FPS games. See the documentation for more data.
A generic game engine built on top of libksd (http://libksd.sourceforge.net/) using the Atlas (http://www.worldforge.org/website/protocols/) for the network protocol.
CheetahWizard is an extension of the Cheetah template engine and code generator. It makes easier the use of Cheetah for the generation of multiple documents from templates in a local environment and provides a Wizard-GUI to fill in necessary information t
Ly: a 'lyterate' programming engine written in Python, featuring an easy-to-read syntax based on indentation. Source files look very similar to the HTML produced from them. Does chunking (arrange the code as you like, not as your compiler wants you to).
Frosttie (FROnt-end SchemaTron Text Internet Engine) takes XHTML pages and processes them with various user-definable filters such a W3C's WAI, Section 508 (US) web usability compliance, ad removal, etc. It can be used with zKnowMan.
Top Engine the Semantic Web Engine for the Enterprise. Top Engine is a Business Rule Engine that utilize OWL DL ontologies for vocabulary primitive to write rules on top of ontology. Top Engine support forward and backward chaining with truth maintenance
Eynhorn is a 3d action rpg engine / framework. It will support dialog system, fight system, armors and weapons, and will include a map assembly. It is realized in Soya 3d and Python, so it'll be platform independent.
Spoor is a lightweight, highly-customizable wiki engine with support for dynamically creating fields for structured data. It is written in Python and utilizes the Django web framework.
Orwell is a debugging engine written in Python and C++. It allows programatic debugging, meaning you can inherit from all of the debugger's classes and add your own functionality. It also aims to provide great support for breakpoints en masse.