Search Results for "finite difference"

...We provide fast objective functions, gradients, and for some cases hessians as well as approximations thereof. As a user, you can easily define custom loss functions. For those, you can decide to provide analytical gradients or use finite difference approximation / automatic differentiation. You can choose to mix loss functions natively found in this package and those you provide. In such cases, you optimize over a sum of different objectives (e.g. ML + Ridge). This strategy also applies to gradients, where you may supply analytic gradients or opt for automatic differentiation or mixed analytical and automatic differentiation. ...

SPSens is a complete software package written in C that estimates parameter sensitivities for stochastic models of chemical and biochemical reaction networks using Monte Carlo (MC) stochastic simulations. It is possible to estimate sensitivities with respect to system parameters using the following algorithms: finite difference methods (crude monte carlo, common reaction path, coupled finite differences); likelihood ratio methods; and regularized pathwise derivatives. Additionally the package includes basic stochastic simulation algorithms. The package includes several example networks which can be easily modified for other networks. Serial and parallel MPI implementations can be built and called from the command line. ...