Pygrid is an open-source and cross-platform pygame/python 2D engine.
The Flixel Power Tools are a set of plug-ins for Flixel 2.5+
A graphics engine + toolkit.
Graph editing tool
Cross platform 2D game creation framework with Python bindings
Gameserver Installer/Startscript for HL1 and HL2 Games
C-Lesh is a game programming language for 2D games.
Access to Irrlicht Engine SDK from assembler, C, Python, Basic, Pascal
Cross-platform reimplementation of AMOS BASIC (runtime)
Multi-Language Wrapper Collection for the Irrlicht Engine
Formerly CraveJs, it's for creating JavaScript applications and games.
A cross-platform OpenGL based lightweight scenegraph library
AMOS BASIC reimplementation in Java
fiftyfifty is a programming language and game
A generic framework for the generation of game levels.