Search Results for "protein"

Chiu et. al., Genome Research 2014 Cupid is a method for simultaneous prediction of miRNA-target interactions and their mediated competitive endogenous RNA (ceRNA) interactions. We showed that our integrative approach significantly improves on miRNA-target prediction accuracy as assessed by both mRNA and protein level measurements in breast cancer cell lines. Cupid is implemented in 3 steps: Step 1: re-evaluate candidate miRNA binding sites in 3’ UTRs, as inferred by TargetScan, miRanda...

The Structural Proteomics Application Development Environment is a Python tool kit for developing and deploying bioinformatics applications. Handles graphics, analysis, and modeling of protein sequence and structure. Source and Win installers available. SPADE source code can be cloned from http://www.github.com/deaconjs/SPADE.

The subgraph matching problem (subgraph isomorphism) is NP-complete. We designed a simple exact subgraph matching (ESM) algorithm for dependency graphs using a backtracking approach. The total worst-case algorithm complexity is O(n^2 * k^n) where n is the number of vertices and k is the vertex degree. We have demonstrated the successful usage of our algorithm in three biomedical relation and event extraction applications: BioNLP 2011 shared tasks on event extraction, Protein-Residue...

Library Of Randomized Algorithms: Randomization is a powerful idea has applications in science and engineering. Difficult optimization problems, protein folding and data mining are only a few of the problems that have been solved using randomization.