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The Virtual Geometry Model (VGM) provides abstract interfaces to geometry objects and functions for conversion between supported geometry formats (Geant4, Root, GDML, AGDD).
This is GEANT4 simulation of such process:
electrons with energy ~45MeV hits the 1.0mm thick plate made of Tl, newly generated gamma along with electrons quants going thru Al 10cm thick material and then they hit 1mm thick Indium-made target, if it's enabled. The result of simulation is a spectra of deposited in target energy (if enabled).