Vamos is an automotive simulation framework with an emphasis on thorough physical modeling and good C++ design. Vamos includes a real-time, first-person, 3D driving application.
MV3D is an open source virtual world simulation framework written in Python. It was designed with scalability in mind and aims to be able to distribute a world across as many servers as needed while dynamically balancing the load.
The COMPASS Engine is a framework for building online games. It aims to use existing web technologies (HTTP, XML, JS) to produce a MVC architecture following RESTful principles.
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pyRobbie is a Robot simulation program, written in Python, which enables users to control a (graphical) Robot through a 2D graphical world to solve different problems. The intent is to provide an easy to use framework for constructing programming example
PyPet is a virtual pet simulation class written in Python, allowing for an open source framework for virtual pets. Includes numerous interfaces including a SuperKaramba theme, as well as supporting remote interaction over the internet or other networks.