file digest
A command-line utility for calculating and verifying file checksums.
... the checksums:
digest -c skein512/256 checksums.skein
You can get a full list of supported algorithms and test the performance of different algorithms on your PC using the command:
digest test <iterations> <filename>
This will calculate hash sum of <filename> multiple times (number of times is specified by <iterations>) and output the results with precise timings.
Note: if you have a 64-bit operating system, use 64-bit binary of the utility, because it is significantly faster for large files.