...The complex binds and then cleaves mRNA molecules of active transposons. The resulting mRNA fragments induce the production of more piRNAs, thus reinforcing the anti-transposon response in a feed-forward loop called the "ping-pong cycle".
A key question in ping-pong cycle research is identification of piRNAs which are amplified through the cycle. PingPongPro is a command-line tool for detecting ping-pong cycle activity in piRNA-Seq data.
PingPongPro was developed at the Institute of Molecular Biology gGmbH in Mainz.
PING is a distributed, web-based, personally controlled electronic medical record system that is accessible to the nomadic user and built to public standards. The PING project includes a pluggable web services API and numerous client applications.