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Bash Framework to combine many preprocessing and alignment tools
DNA and RNA nucleotide sequences are an ubiquitous element of all biological cells and are serving on one hand as a comprehensive library of capabilities for the cells and on the other as an impressive regulatory system to control cellular function. The presented multi-alignment framework (MAF) should give researchers a simple sequence alignment platform as a functional template, flexible enough to adjust all steps but also comprehensive enough to join many different tools and custom parameter combinations if in-depth analysis is necessary or advised in e.g. low read rate situations. ...
The developed graphical interface is based on the SKILL language which is a Lisp dialect used as a scripting language and PCell (Parameterized Cells) description language used in many EDA software suites by Cadence Design Systems.
Unix-based preparation and analysis toolbox for molecular simulations
...The toolbox is to be understood as a scripting framework rather than a black-box software.
Task specific input and preparation or analysisfunction, are easy expandable to meet the scientific characteristic of constant changing properties.
Concepts for efficiently storing and analysing large files in conjunction with graphical visualization and numerical data processing are presented in a Manual.
A documented script collection that allows reproducing all simulations and analysis results presented in the Doctoral thesis of the author.
FFP (Feature frequency profile) is an alignment free comparison tool for phylogenetic analysis and text comparison. It can be applied to nucleotide sequences, complete genomes, proteomes and even used for text comparison.
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