Search Results for "dose"

TAVIA is a free and open-source desktop application for statistical analysis, scientific graphing, reproducible workflows, and research project management. It combines editable data tables, statistical tests, regression, dose-response analysis, publication-quality graphs, reports, project history, and reproducibility tools in one workspace. Analyses and graphs remain linked to their source data so results can be refreshed when data changes. TAVIA supports Windows, Linux, and macOS, includes a command-line analysis interface, encrypted project files, plugin support, automatic update checking, and built-in documentation. ...

Physiologically based toxicokinetic (PBTK) modeling offers great promise in environmental risk assessment, potentially speeding up dose-response studies while minimizing animal testing. Some limitations exist in the PBTK field, such as difficulty of model development and a lack of application specific software tools to help modelers. Some parameters used in PBTK models, such as tissue weights, are easily measure. Other parameters can be determined through in-vitro experiments or through extrapolation using published equations. ...

Objective: The program is being developed for three main purposes: A. Dose assessment after acute whole body exposure. B. Dose assessment in partial body exposure C. Dose assessment after protracted and fractioned exposure 2. Applicability The following DNA lesions can be investigated with the help of the program: A. Dicentrics B. γ-H2AX foci C. Micronuclei D. PCC fragments It is planned to include Comet assays as well RICA assays in the future.

ABE is a small, fast and convenient program for visualizing and modeling experimental bioassay data. The data can be modeled using either polynomials or a more specific four-parameter model based upon the standard, sigmoidal dose-response curve.