Search Results for "active tcl"

.... Users can write programs in its native programming language, and many have contributed useful packages in a variety of areas over the decades. Maxima is GPL-licensed and largely written in Common Lisp. Executables can be downloaded for Windows, Mac, Linux, and Android; source code is also available. An active community maintains and extends the system. Maxima is widely used. Additional add-on packages for Maxima can be found at: https://github.com/maxima-project-on-github/maxima-packages

... of correlated motions leading from the allosteric to the primary active site. We present a program called Weighted Implementation of Suboptimal Paths (WISP) capable of rapidly identifying additional suboptimal pathways that may also play important roles in the transmission of allosteric signals. Aside from providing signal redundancy, suboptimal paths traverse residues that, if disrupted through pharmacological or mutational means, could modulate the allosteric regulation of important drug targets.