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...When you are looking to start Qiskit, you have two options. You can start Qiskit locally, which is much more secure and private, or you get started with Jupyter Notebooks hosted in IBM Quantum Lab. Qiskit includes a comprehensive set of quantum gates and a variety of pre-built circuits so users at all levels can use Qiskit for research and application development. The transpiler translates Qiskit code into an optimized circuit using a backend’s native gate set, allowing users to program for any quantum processor or processor architecture with minimal inputs. ...

ProjectQ is an open-source effort for quantum computing. It features a compilation framework capable of targeting various types of hardware, a high-performance quantum computer simulator with emulation capabilities, and various compiler plug-ins.