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Pygme is an mplayer frontend written in Python/PyGTK. Pygme has a searchable media library (similar to winamp), a playlist and has ID3 tagging support. It uses sqlite through pysqlite bindings to maintain media lib and playlists.
yuik is an abstract widget library for creating GUIs. The actual frontend can be chosen at runtime which allows the program to run under Tk, as a shell program, and even as a web-application. More frontends like an irc-bot, wxWidgets, or XUL are planned.
AFX is an X11-based, extensible, graphical, and highly configurable frontend primarily for use on tv-connected systems. The original design goal is a joystick-controlled frontend for an entertainment (games, emulators, audio, and video) box.
Automatic File type converter Daemon - automatically converts the file type while renaming a file, based on the source and destination file extension. Currently it supports conversion for image types and provides a GTK+ frontend.
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Jack is a text mode (optionally curses) CDDA extraction / MP3 encoder frontend with features like freedb query, continue mode, customizability and many more
Python-based editor framework that is by design display agnostic. It will be able to edit files in virtually any display framework from curses to OpenGL, as long as there exists a frontend for it.
Frontend or sc_trans, written in wxPython, built in playlist editor, and transmit button to start streaming directly from the frontend. supports freebsd and macosx, send kill signals directly from the frontend too!
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MovieShare is a filesharing application for movies. It uses Imdb information as its frontend, and uses the BitTorrent technology to download the files.
It requires python, wxpython and PythonCardPrototype 0.7.
Working as a courier-mta frontend, QUICA can make a quick and friendly to use mail server. Tasks like creating accounts and forwards can be done easily. QUICA manages domains separately , allowing the delegation of each domain to different people.
CabFE is a multi-emulator frontend for MAME, Daphne and other arcade games designed specifically for arcade cabinets using minimal set of controls (typically only a joystick and a few buttons) that are common on cabinets.
Classicollect is an SQL schema and data entry frontend for cataloguing
a classical CD collection. It is written in Python and uses
Postgresql for the database backend and gnome-python for user
interface. Currently it runs in the GNOME environment.
Puke is a jukebox style curses frontend for mpg123 or mpg321 written in python. Its main feature is the ability to search for songs and queue them up for play. If there are no songs queued it will play a random song.
CvsShell is a console-based cvs frontend. It provides convenient access to the cvs commands through a shell-like user interface. CvsShell is written in Python.
wxCvs is a cross-platform GUI frontend to the GNU Concurrent Versioning System (CVS). It is written in python and uses bindings to the wxWindows C++ cross-platform GUI toolkit (http://wxwindows.org). The python bindings to wxWindows is known as wxPyton
Metagame-Sector is a Python framework for quickly and easily making Sector-based games (ie, Chess, Risk, Bard's Tale, Zelda, WarCraft, Civ). Features include Client-Server model, View separation (ie, you can have a GNOME and a Win32 frontend), and more.
This is the linux GUI for the eDonkey2000 project, u still
need the command line client but if u download this tool u will
have a nice frontend too to make it handy
A cross-platform emulators frontend with ROMs database support.
Start-Game T00L is a cross-platform emulator frontend and ROM manager coded in Python using a Pyglet-based interface.
It's still on a very early stage of development, and most of the features are not implemented yet.
The goal is to make a fully functional frontend which works straight out of the box, without the need to configure every single emulator (like you need to do in every other frontend today).