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Spineless is a generic cross-platform 3D game engine implemented in Python. Focus is on flexibility, clean design and ease of use, not pure speed or bleeding edge graphics.
Tk-based standalone graphing system and extensible graphing library with a huge range of 2d modes (maybe 3d soon?) written in Python (Python/Tk are 100% cross platform)
RADAR is a pluggable network monitoring platform that allows for reporting and searching at the application layer. Out of the box, RADAR lets you capture SMTP, AIM, YahooIM and YMail traffic. Find out more at: http://www.optaros.com/solutions_radar.html
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Beatbox is a cross platform application written in Python and using the wxPython widget library. It was created out of necessity, I had all my DJ tracks burned on CDs in no real order, so I've decided to write this app to help me easily find which trac
Spike Asset Manager (SAM) is an open-source cross-platform framework for probing a system for components and reporting them. It includes a driver file that probes for components commonly found in a LAMPJ stack (Apache, MySQL, PHP, Tomcat, etc).
openSputnik is a robust distributed platform for massive scale precalculation of genetic and genomic data using contemporary bioinformatics methods. Annotated DNA, RNA and protein sequences are stored as binary objects in a variery of relational database
Smart Card developmennt environment (cross-platform software and smart card applets for Javacard and BasicCard).
SCF Bundle provide everything but the GUI to develop a smart card based application.
The CCC Language is yet another programming language. It is platform-independent, compact, and robust. Supports many SQL engines, has own ISAM DB engine, has terminal mode and more UI-s, is object-oriented, but it is compiled and not interpreted.
PyUI2 is a cross platform user interface library written in Python. It is targeted primarily for game development, but can be used as a user interface for other applications.This version has been forked from the original Pyui library.
Medical Image Computing Workflow (MICFlow) is a simple, easy but flexible, extensible and powerful workflow system to automate medical image computing tasks such as segmentation, registration and analysis. It's pure Python so can be used on any platform
PyDespike is a cross platform (Windows, Mac, Linux) program written in Python using the PyQt and PyQwt libraries used to graphically process (despike) raman or other spectroscopic data in an efficient manner.
Marvin3 is a new cross-platform stack-based language developed in Python. Marvin3 features object-oriented-programming, anonymous routines, eager lists, variables, lexical scope, combinators and support for modules.
...The tool should provide a simple way to log the user's mouse movements in the background for (later) analysis. Currently only for Mac OS X (ObjC & Cocoa), planned to make platform independent with Python. It consists out of two
Traditional but powerful cross-platform calculator. It is written in python and it uses wxWidgets as GUI (project is developed with Boa Constructor). By use of SciPy the vaCalculator can solve linear systems, do math with polynomials, integration etc.
MayaVi is a free, cross platform, easy to use scientific data visualizer. It provides a GUI to ease the visualization process, is written in Python and uses the Visualization Toolkit (VTK) for the graphics.