Jellyfish Quest is an adventuregame in which you play as a jellyfish out to rescue your girlfriend from Japanese fishermen. Features the flexible game mechanic of grabbing stuff with your tentacles, a rather silly plot, and tiny, tiny, graphics.
Reign of the Wizard is a text-based strategy game written in Python, inspired by other text adventures such as The Colossal Cave Adventure and Nethack.
PyTaco is a text adventure development framework written in Python. PyTaco is currently in development and at the moment only features a basic game engine and XML configuration files for rooms.
"Helvin Space Trip" is a click and play graphical adventuregame similar to the classical Sierra Monkey Island style games.
It is coded entirely in python.
Pyzzle is a cross-platform game engine for creating large-scale, 2D Myst-like adventure games. The engine supports 2D panoramas, features an intuitive design mode, and allows users to download content from the internet. Pyzzle is written using Pygame.
The Crime Tracer is an adventure crime game. The main character of the game is a detective who is investigating several crime cases while trying to arrest a professional serial killer.
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AdventureGame Goddess (aka FEAGS) is a Frontend for AGS AdventureGame Studio * Database with hundreds of adventure games * Search, Filter and sort functions * One click: the game is downloaded, installed and set up. One click: you are playing
An integrated tile-based map editor, game engine and cross-platform installation suite using Python and Pygame (SDL) [installation suite not in current release]
Lart Wars is a text based role-playing game where the player starts as a computer enthusiast and gradually moves up in levels to a BOFH based on experience points.
Graphical AdventureGame Engine(GAGE) is a simple engine for creating 2D point-and-click graphical adventure games. The engine can also be used to create other genres of 2D games.
Packdude is a Pacman clone for Linux and other unix like systems that offers some new features like scripting language (namely Python) and adventure style storyline.