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PyWebMail is a Python library and POP3 gateway that enable working with WebMail servers like with POP3 or IMAP mail server. Currently Mail.Com, Yahoo! Mail, Gmail, Netscape.Net, HotMail and some minor servers support is finished.
Gnoptray is a mail notification utility for GNOME, that will support multiple accounts. It will sit in the notification area and display a total e-mail count. Hopefully, it will do a better job of previewing e-mail than current 'biff' like programs.
Active Spam Killer for Windows (AfW) is a challenge/response spam filtering system for the Windows platform. Based on ASK for Linux by Marco Paganini, this project adds a POP3 client/server wrapper and web administration, as well as Windows compatibility
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JEEPERS (Jason's Extra Easy to Program Email Response System) uses a POP3 email account to monitor email for command phrases in subject lines. Default commands for remote file storeage and retrival. (Nothing to do with mailing lists or mass emailing.)