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Hedwig is an open source IMAP, SMTP, POP3 server written in Java, designed with ease of installation and configuration in mind. Hedwig enables storage of mail message headers in a relational database(MySQL or Oracle) and mail messages in a file system.
Visit http://hwmail.sourceforge.net/ for more information.
NEXUSe2e client is an Eclipse RCP application that provides XML based messaging using e.g. ebXML to integrate business processes that span multiple companies. It enables small organizations to participate in supply chain integration scenarios.
PyWebMail is a Python library and POP3 gateway that enable working with WebMail servers like with POP3 or IMAP mail server. Currently Mail.Com, Yahoo! Mail, Gmail, Netscape.Net, HotMail and some minor servers support is finished.
Tortoise Mail is a POP3 and SMTP E-Mail Client written in PHP. By using PEAR Package DB, it supports many SQL-Based Databases (dbase, fbsql, ibase, ifx, msql, mssql, mysql, oci8, odbc, pgsql, sqlite, sybase). It is also PHP 5.x compatible.