See https://github.com/sitefusion
SiteFusion is a server-based development environment. Applications are written in PHP and work through a thin XUL client. SiteFusion applications look and behave like native system applications but run on a server generating JavaScript commands.
A platform for web sites and services that require solid support for rich user interfaces in a fail-safe and scalable architecture. It consists of a frontend Javascript framework (also usable stand-alone) and a backend PHP/MySQL environment.