See https://github.com/sitefusion
SiteFusion is a server-based development environment. Applications are written in PHP and work through a thin XUL client. SiteFusion applications look and behave like native system applications but run on a server generating JavaScript commands.
The xWire framework is a toolkit used to build Java web applications, but is flexible enough for other uses. It is ideal for building AJAX apps and consists of both client and server components, each of which can be used independently of the other.