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...Yapsy v2+ supports Python 3 and it's development happens now on https://github.com/tibonihoo/yapsy/
Usage samples, advices and developer's documentations are available on the main website.
NOTE: PythonQt has been moved to https://github.com/MeVisLab/pythonqt
PythonQt is a dynamic and lightweight script binding of the Qt framework to the Python language. It can be easily embedded into Qt applications and makes any QObject derived object scriptable via Python without the need of wrapper code generation.
Additional Graphical Classes and Widgets for Tkinter/Ttk
This is a Python package with extensions for Tkinter. It supports both Python 2.7 and Python 3.3. Currently, the project is in version 1.0 of the Production stage. Feel free to fork off the main project or send me possible additions to the package.
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Aurora Application Server is a new Python Web Application Server and Framework. The main goal of the project is to provide the developer with a complete set of tools to speed up the application development process. See project wiki for more information.
AALib/PyAALib - Asynchronous Action Library Project - The project is a Framework based on Pure Object Oriented Concepts to develop asynchronous communication between threads (thread safety) and external process. Platforms: Windows, MacOSX, Linux,Sola
A platform independent framework to remote control Lego Mindstorms NXT from Python.
Using PyBluez http://org.csail.mit.edu/pybluez/ for Bluetooth connectivity and wxPython http://www.wxpython.org/ for UI.
ACDK - Artefaktur Component Development Kit - is a platform independent C++-framework similar to Java or C#/.NET for generating distributed and scriptable components and applications.
Educational game framework supporting board games, strategy games, and other grid-based game boards. Currently uses Python/wxPython as the application language/library. C++ libs included to help create AI for the various games.
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TurboGears 2 is a web framework, but unlike some of its competitors, it's not a monolithic unit, it's a collection of libraries, WSGI components, and web development tools that works well together and is configured to provide a great out of the box.