...Currently Pony works with SQLite, MySQL, PostgreSQL and Oracle databases.
Pony ORM also include the ER Diagram Editor which is a great tool for prototyping. You can create your ER diagram online at https://editor.ponyorm.com, generate the database schema based on the diagram and start working with the database using declarative queries in seconds.
FreeGee is an integrated application framework for Python and C++. Included modules are: Python (scripting), PostgreSQL (database), wxWidgets/wxWindows (GUI), GnuPG (crypto), omniORB (OO middleware), Apache (Web), and other fine tools (see Home Page).