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CyberMed is a framework for the development of medical simulations based on virtual reality. It includes support to visualization, haptics, deformation, stereoscopy, collision detection, user assessment, texturing, tracking and collaboration.
PixelLight is a cross-platform application framework
PixelLight is a cross-platform application framework for any kind of 3D applications like games, interactivesimulations or visualizations. It's written in C++ and has been designed with flexibility and extensibility as one of it's main goals.
Aesthe is 3D scripting development environment controlled by command line with built-in 3D modeller, allowing you to create interactive script-driven 3D simulations or animations.
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Ruby-Newton is a Ruby wrapper for the NewtonGameDynamics physics engine ( http://newtondynamics.com/ ) It brings object-oriented real-time animated physics simulations to Ruby-enabled applications (e.g. 3D modeling tool with interactive scripting support