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Human protein similarity network used to predict drug safety.
This is the protein similarity network - PSIN. Here, the nodes are human proteins and they are linked only if they share considerable sequence similarity.
We found that this network is particularly useful to distinguish approved from problematic drug-targets.
Here you also find the complete set of programs and datasets we used for this purpose.
Free to help further test and develop this project. Your help and expertise are much appreciated !
If you have any questions, please do...
A set of tools for working with high-throughput sequencing data
A set of tools (in Java) for working with next generation sequencing data in the SAM/BAM format. Note that development has moved to GitHub at https://github.com/broadinstitute/picard and support is available on the GATK forum at http://gatkforums.broadinstitute.org/categories/ask-the-team
Modern MATLAB-based modelling software for 13C metabolic flux analysis (MFA).
Support available in Google group (https://groups.google.com/d/forum/13cmfa-openflux).
Cca-forum unifies the Common Component Architecture tools and tutorial. It includes the CCA specifications, the Ccaffeine framework for HPC, and related tools. These support multilanguage scientific and parallel computing.
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