...Both simulation tools require to be run on a Windows platform.
Fortunately Microsoft has also released a command line version for Linux and Mac OS based on OCAML however this version will only output a CSV file for the simulation results.
SPiM2Eclipse provides a bridge for those running SPiM from the command-line by allowing simulations to be completed by a single click, displaying an embedded plot of the results.
Features:
-As an Eclipse plugin you have all of the powerful features of Eclipse available to you.
-Syntax color highlighting
-One-click simulation with plotting
For more information on SPiM see the offical project website at: http://research.microsoft.com/en-us/projects/spim/