Wars of the Elder races is the most far-out MMORPG that I can think of. Characters will start on earth and have to level up {like World of Warcraft). Since it involves the Elder race theory, you will evolve as a being that can travel the cosmos!
Independency will be a browser game set in space. It is written from scratch and uses Java Servlet Tech. Gameplay will be like OGame, but with more features.
Decimation is an open-source multiplayer game framework programmed in Java. It can support a variety of 3D games, ranging from small four-person games to large massively multiplayer online role-playing games, supporting thousands of concurrent users.
Wiso is a Iso web framework written in HTML/Javascript/CSS based on the Prototype framework. Wiso can be part of a 2.5D (isometry) web game engine for web games.
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It's a browser based space mmorpg game called Pulsar Online. It was launched in mid 2011. Game is playable, functional, although it lacks some planned and required features like port raiding, better UI, more RPG and so on. All PHP developers are welcome to develop new functions and fix old bugs.